The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2018
Filed:
May. 17, 2014
Applicant:
Forschungszentrum Juelich Gmbh, Juelich, DE;
Inventors:
Doerte Rother, Huerth, DE;
Martina Pohl, Aachen, DE;
Torsten Sehl, Juelich, DE;
Alvaro Gomez Baraibar, BE Delft, NL;
Assignee:
Forschungszentrum Juelich GmbH, Juelich, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/00 (2006.01); C12P 7/26 (2006.01); C12P 13/00 (2006.01); C12N 9/10 (2006.01);
U.S. Cl.
CPC ...
C12P 13/001 (2013.01); C12N 9/1096 (2013.01); C12Y 206/01062 (2013.01); C12Y 401/01001 (2013.01); C12P 7/26 (2013.01); C12Y 206/01 (2013.01);
Abstract
A method for producing cathine ((1S,2S)-norpseudoephedrine), in which, in a first reaction step, benzaldehyde is reacted with an acetyl donor according to formula (1), where R═H or COOH, by way of an (S)-selective lease to yield an enantiomer mixture according to formulas (2) and (3) and, in a second step, the compound according to formula (3) is reacted with an amine donor by way of an (S)-selective transaminase to yield (1S,2S)-norpseudoephedrine.