The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 13, 2018

Filed:

Aug. 21, 2013
Applicant:

Bioamber Inc., Plymouth, MN (US);

Inventor:

Man Kit Lau, Minneapolis, MN (US);

Assignee:

BIOAMBER INC., St. Paul, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 13/00 (2006.01); C12N 9/04 (2006.01); C12N 9/88 (2006.01); C12N 9/06 (2006.01); C12N 9/02 (2006.01); C12N 9/10 (2006.01); C12N 9/00 (2006.01); C12P 13/04 (2006.01); C12N 9/16 (2006.01);
U.S. Cl.
CPC ...
C12P 13/001 (2013.01); C12N 9/001 (2013.01); C12N 9/0006 (2013.01); C12N 9/0008 (2013.01); C12N 9/0016 (2013.01); C12N 9/1096 (2013.01); C12N 9/13 (2013.01); C12N 9/16 (2013.01); C12N 9/88 (2013.01); C12N 9/93 (2013.01); C12P 13/005 (2013.01); C12P 13/04 (2013.01);
Abstract

A chemical having the formula (S) 2-amino-6-hydroxypimelate. (S)-2-amino-6-hydroxypimelate can be made using a method comprising culturing a cell comprising an exogenous nucleic acid sequence encoding an enzyme that catalyzes the substrate to product conversion of (S)-2-amino-6-oxopimelate to (S)-2-amino-6-hydroxypimelate and separating the (S)-2-amino-6-hydroxypimelate. The cell may be a recombinant microorganism for producing aminocaproic acid or hexamethylenediamine from (S)-2-amino-6-hydroxypimelate comprising at least one exogenous nucleic acid sequence that expresses at least one polypeptide with substrate preference for homolysine, and amino acid decarboxylase with substrate preference for alpha-aminopimelate.


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