The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 13, 2018

Filed:

Aug. 19, 2013
Applicant:

Kaneka Corporation, Osaka-shi, Osaka, JP;

Inventor:

Kazunobu Minakuchi, Takasago, JP;

Assignee:

KANEKA CORPORATION, Osaka, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 1/16 (2006.01); C07K 1/18 (2006.01); C07K 1/22 (2006.01); B01J 39/26 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
C07K 1/165 (2013.01); B01J 39/26 (2013.01); C07K 16/00 (2013.01); C07K 1/18 (2013.01); C07K 1/22 (2013.01);
Abstract

A mixed mode antibody affinity separation matrix comprises an antibody affinity ligand and a cation exchange group on a single separation matrix. According to such a matrix in the first step of a process for purifying an antibody or an Fc-containing target molecule, the antibody as the main target substance of the affinity purification can be purified at high purity, the selective separation properties of monomers can also be improved; and the burden on a subsequent impurity removal step can be reduced with respect to the removal of impurities such as aggregates.


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