The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2018
Filed:
Dec. 08, 2014
Ucb Biopharma Sprl, Brussels, BE;
Rikki Peter Alexander, Slough, GB;
Julien Alistair Brown, Slough, GB;
Michael Deligny, Brussels, BE;
Jag Paul Heer, Brussels, BE;
Victoria Elizabeth Jackson, Slough, GB;
Sophie Jadot, Brussels, BE;
Boris Kroeplien, Slough, GB;
Malcolm Mac Coss, Seabrook Island, SC (US);
Yogesh Anil Sabnis, Brussels, BE;
Dominique Louis Léon Swinnen, Brussels, BE;
Nathalie Van Houtvin, Brussels, BE;
Zhaoning Zhu, Slough, GB;
UCB BIOPHARMA SPRL, Brussels, BE;
Abstract
A series of substituted fused tricyclic imidazole derivatives, in particular dihydro-1H-pyrano[4',3′:4,5]imidazo[1,2-a]pyridine, 1,2,3,4-tetrahydroimidazo[1,2-a:5,4-c′]dipyridine, dihydro-1H-pyrano[3′,4′:4,5]imidazo[1,2-a]pyridine and tetrahydro-6H-cyclohepta[4,5]imidazo[1,2-a]pyridine, and analogs thereof, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.