The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2018
Filed:
Jun. 05, 2014
Synthon Biopharmaceuticals B.v., Nijmegen, NL;
Tijl Huijbregts, Nijmegen, NL;
Ronald Christiaan Elgersma, Nijmegen, NL;
Patrick Henry Beusker, Nijmegen, NL;
Johannes Albertus Frederikus Joosten, Nijmegen, NL;
Rudy Gerardus Elisabeth Coumans, Nijmegen, NL;
Henri Johannes Spijker, Nijmegen, NL;
Wiro Menge, Nijmegen, NL;
Franciscus Marinus Hendrikus De Groot, Nijmegen, NL;
Synthon Biopharmaceuticals B.V., Nijmegen, NL;
Abstract
The present invention relates to a process comprising converting a compound of formula (I) into a compound of formula (II) by reaction with an organolithium reagent, which compound can be further converted into duocarmycin analogs consisting of a DNA-alkylating and a DNA-binding part, and still further into corresponding antibody-drug conjugates.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile