The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 13, 2018

Filed:

Feb. 26, 2015
Applicant:

Ono Pharmaceutical Co., Ltd., Osaka, JP;

Inventors:

Seiji Ogawa, Osaka, JP;

Toshihide Watanabe, Osaka, JP;

Isamu Sugimoto, Osaka, JP;

Kousuke Tani, Osaka, JP;

Kazumi Moriyuki, Osaka, JP;

Yoshikazu Goto, Osaka, JP;

Shinsaku Yamane, Osaka, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/12 (2006.01); C07D 417/04 (2006.01); C07D 407/04 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 417/04 (2013.01); A61K 45/06 (2013.01); C07D 407/04 (2013.01); C07D 417/12 (2013.01);
Abstract

A compound represented by general formula (I) wherein all symbols are as defined in the specification, a salt or N-oxide of the compound, or a solvate or prodrug of the compound or the salt or N-oxide has a selective EP2 agonist activity and is highly safe, and is therefore useful as a drug, especially as a therapeutic agent for EP2 receptor-related diseases including immune diseases, allergic diseases, neuronal death, dysmenorrhea, premature birth, miscarriage, baldness, ocular diseases, erectile dysfunction, arthritis, lung injury, pulmonary fibrosis, pulmonary emphysema, bronchitis, chronic obstructive pulmonary disease, bone diseases, cartilage injury and others.


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