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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9890145 B1

PDFFull Text
Date of Patent:
Feb. 13, 2018

Filed:

Apr. 25, 2016

Heterocyclic compound

Applicant:

Takeda Pharmaceutical Company Limited, Chuo-ku, Osaka-shi, Osaka, JP;

Inventors:

Masato Yoshida, Kanagawa, JP;

Kazuaki Takami, Kanagawa, JP;

Yusuke Tominari, Kanagawa, JP;

Zenyu Shiokawa, Kanagawa, JP;

Akito Shibuya, Kanagawa, JP;

Yusuke Sasaki, Kanagawa, JP;

Tony Gibson, San Diego, CA (US);

Terufumi Takagi, Kanagawa, JP;

Assignee:

Takeda Pharmaceutical Company Limited, Osaka, JP;

Attorney:

Foley & Lardner LLP

Primary Examiner:

Daniel Carcanague

Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 487/04 (2006.01); C07D 417/14 (2006.01); C07D 487/10 (2006.01); A61P 37/00 (2006.01); C07D 403/14 (2006.01); A61K 31/4155 (2006.01); C07D 413/14 (2006.01); C07D 401/04 (2006.01); C07D 409/14 (2006.01); C07D 405/14 (2006.01); A61K 9/06 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); C07D 403/04 (2006.01); C07D 471/04 (2006.01); C07D 471/10 (2006.01); C07D 491/107 (2006.01); C07D 495/04 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); A61K 9/06 (2013.01); A61K 9/2018 (2013.01); A61K 9/2054 (2013.01); A61K 9/4858 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 471/10 (2013.01); C07D 487/04 (2013.01); C07D 487/10 (2013.01); C07D 491/107 (2013.01); C07D 495/04 (2013.01);
Abstract

The present invention provides a heterocyclic compound having an IRAK-4 inhibitory action, which is useful for the prophylaxis or treatment of inflammatory disease, autoimmune disease, osteoarticular degenerative disease, neoplastic disease and the like, and a medicament containing thereof. The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.

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