The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2018
Filed:
Feb. 05, 2015
Applicant:
Kaohsiung Medical University, Kaohsiung, TW;
Inventors:
Mei-Ling Ho, Kaohsiung, TW;
Je-Ken Chang, Kaohsiung, TW;
Rajalakshmanan Eswaramoorthy, Kaohsiung, TW;
Shun-Cheng Wu, Kaohsiung, TW;
Yao-Hsien Wang, Kaohsiung, TW;
Assignee:
KAOHSIUNG MEDICAL UNIVERSITY, Kaohsiung, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/18 (2006.01); A61L 27/54 (2006.01); A61L 27/56 (2006.01); C08J 9/26 (2006.01); C08G 63/91 (2006.01); C12N 5/0775 (2010.01);
U.S. Cl.
CPC ...
A61L 27/18 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); C08G 63/912 (2013.01); C08J 9/26 (2013.01); C12N 5/0667 (2013.01); A61L 2430/02 (2013.01); C08J 2201/0446 (2013.01); C08J 2207/10 (2013.01); C08J 2367/04 (2013.01); C12N 2500/42 (2013.01); C12N 2501/999 (2013.01); C12N 2533/40 (2013.01); C12N 2537/10 (2013.01); Y10T 428/2982 (2015.01);
Abstract
A method for bone regeneration which comprises administering a short term release composition into a bone area of a subject in need thereof, wherein the composition comprises a poly(lactic-co-glycolic acid) cross-linked alendronate (PLGA-ALN), wherein the composition releases the alendronate into the bone area, wherein the bone tissue of the bone area is exposed in situ to a therapeutically effective amount of the alendronate over 9 days.