The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2018
Filed:
Dec. 16, 2016
Cytomx Therapeutics, Inc., South San Francisco, CA (US);
Henry Bernard Lowman, El Granada, CA (US);
Luc Roland Desnoyers, San Francisco, CA (US);
Shouchun Liu, Burlingame, CA (US);
James William West, San Mateo, CA (US);
Jason Gary Sagert, San Mateo, CA (US);
Olga Vasiljeva, Cupertino, CA (US);
Elizabeth-Edna Mary Menendez, San Mateo, CA (US);
CYTOMX THERAPEUTICS, INC., South San Francisco, CA (US);
Abstract
The invention relates generally to activatable antibodies that include a masking moiety (MM), a cleavable moiety (CM), and an antibody (AB) that specifically binds to epidermal growth factor receptor (EGFR), and to methods of making and using these anti-EGFR activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.