The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2018
Filed:
Sep. 15, 2010
Applicants:
Jeffrey D. Esko, San Diego, CA (US);
Yitzhak Tor, San Diego, CA (US);
Inventors:
Jeffrey D. Esko, San Diego, CA (US);
Yitzhak Tor, San Diego, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/54 (2006.01); A61K 38/47 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 38/47 (2013.01); A61K 47/4823 (2013.01); A61K 47/48092 (2013.01); C12Y 302/01031 (2013.01);
Abstract
Reagents and methods useful for the synthesis of conjugates comprising guanidinylated cyclic acetals are provided. Also provided are methods for increasing the cellular uptake of various therapeutic compounds and treatment modalities using these conjugates.