The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 06, 2018

Filed:

Jul. 15, 2015
Applicant:

The Buck Institute for Age Research, Novato, CA (US);

Inventors:

Kayvan R. Niazi, Los Angeles, CA (US);

Shahrooz Rabizadeh, Los Angeles, CA (US);

Dale E. Bredesen, Novato, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/00 (2006.01); G01N 33/50 (2006.01); A61K 31/365 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5023 (2013.01); A61K 31/365 (2013.01); A61K 39/0011 (2013.01); A61K 2039/5154 (2013.01); G01N 2333/90241 (2013.01); G01N 2500/10 (2013.01);
Abstract

The invention generally relates to the prevention and/or treatment of cancer, and, more specifically, to the treatment of tumors, including solid tumors and their metastases, without radiation or standard chemotherapeutic agents. In one embodiment, the invention involves a method comprising: a) providing a subject with tumor cells, b) removing at least a portion of said tumor cells from said subject to create removed cells, c) treating at least a portion of said removed cells ex vivo, using stimulating agents, including thapsigargin and/or thapsigargin-related compounds, so as to create treated tumor cells; and d) introducing said treated tumor cells (or fragments thereof) in vivo into the same subject to generate anticancer therapeutic effects.


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