The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 06, 2018

Filed:

Dec. 03, 2012
Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Allen Dale Everett, Glenwood, MD (US);

Howard Katz, Owings Mills, MD (US);

Kalpana Besar, Baltimore, MD (US);

Weiguo Huang, Baltimore, MD (US);

Assignee:

THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/1486 (2006.01); G01N 33/50 (2006.01); G01N 27/327 (2006.01); G01N 27/414 (2006.01); A61B 5/145 (2006.01); C23C 16/448 (2006.01);
U.S. Cl.
CPC ...
G01N 27/327 (2013.01); A61B 5/14507 (2013.01); A61B 5/14865 (2013.01); C23C 16/4486 (2013.01); G01N 27/4145 (2013.01);
Abstract

Disclosed herein are biosensor systems and related methods for detecting analytes in aqueous and biologic environments. A biosensor system for detecting binding of an analyte of interest may include a detector configured to detect a change in an electrical property on a surface thereof. The detector may be a FET. The system also may include a passive layer disposed on a top surface of the detector. Further, the system may include a hydrophobic layer disposed on the passive layer. The system also may include a receptor-attachment material configured for binding to an analyte. A receptor may bind to the analyte, and the receptor may be attached to the receptor-attachment material. The binding of the analyte to the receptor can cause the change of the electrical property at the surface. In response to the change for example, a current may change for indicating the binding of the analyte to the receptor.


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