The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 06, 2018

Filed:

Jul. 02, 2013
Applicants:

Centre National DE LA Recherche Scientifique, Paris, FR;

Institut Curie, Paris, FR;

Universite Pierre ET Marie Curie, Paris, FR;

Inventors:

Jean-Louis Viovy, Paris, FR;

François Amblard, Paris, FR;

Laurent Malaquin, Linas, FR;

Bastien Venzac, Le Mee sur Seine, FR;

Mohamed Lemine Diakite, Grenoble, FR;

Stephanie Descroix, Paris, FR;

Ismaïl Cisse, Aubervillers, FR;

Ulrich Bockelmann, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 21/17 (2006.01); G01N 30/00 (2006.01); G01N 33/487 (2006.01); G01N 15/06 (2006.01); G01N 15/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/686 (2013.01); C12Q 1/6825 (2013.01); G01N 15/0656 (2013.01); G01N 21/17 (2013.01); G01N 30/00 (2013.01); G01N 33/48721 (2013.01); G01N 2015/0038 (2013.01);
Abstract

The present invention concerns a method of detecting macroions in a liquid medium contained in a space, the method including: a) submitting the liquid medium to a stimulating electrical field to induce formation of aggregates of macroions, the formed aggregates of macroions preferably not including any additional labeling agent, and b) measuring, in a detection zone of the space, spatial and/or temporal fluctuations within the liquid medium of at least one variable depending on the concentration of the macroions in the liquid medium, and c) determining, based on these fluctuations, the presence of the macroions, step c) preferably including processing by a time-dependent or space dependent analysis, more preferably by wavelet analysis, or by autocorrelation the fluctuations measured at step b).


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