The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 06, 2018

Filed:

Feb. 17, 2016
Applicant:

Antisense Therapeutics Ltd, Toorak, Victoria, AU;

Inventor:

George Tachas, Kew, AU;

Assignee:

Antisense Therapeutic, Ltd, Toorak, Victoria, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 31/7125 (2006.01); A61K 31/7105 (2006.01); A61K 35/28 (2015.01); A61K 38/19 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1138 (2013.01); A61K 31/7105 (2013.01); A61K 31/7125 (2013.01); A61K 35/28 (2013.01); A61K 38/193 (2013.01); C12N 2310/11 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/322 (2013.01); C12N 2310/3341 (2013.01); C12N 2310/341 (2013.01); C12N 2310/344 (2013.01); C12N 2310/346 (2013.01);
Abstract

The present disclosure relates to a method for treatment or prevention of diseases have an increased level of insulin-like growth factor I (IGF-I). The method comprises administration of a growth hormone (GH) variant having antagonistic activity in combination with an oligonucleotide targeted to growth hormone receptor (GHR) to a subject in need.


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