The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2018
Filed:
Mar. 21, 2017
Applicant:
Nestec S.a., Vevey, CH;
Inventor:
Nicholas Chi-Kwan Ling, San Diego, CA (US);
Assignee:
Nestec S.A., Vevey, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/64 (2006.01); A61K 38/00 (2006.01); C07K 16/32 (2006.01); A61K 47/48 (2006.01); C07K 14/82 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C07K 16/32 (2013.01); A61K 47/48569 (2013.01); C07K 14/82 (2013.01); G01N 33/57415 (2013.01); C07K 2317/24 (2013.01);
Abstract
The present invention provides cyclic peptides comprising a dimer of peptides, each peptide comprising a sequence corresponding to the HER2 splice variant HER2Delta16, wherein the cyclic peptide is cyclized via a disulfide bond between the peptides and via an amino acid linking the peptides. The invention also provides methods of making antibodies that specifically bind to HER2Delta16 homodimers using said cyclic peptides.