The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2018
Filed:
Feb. 11, 2016
Applicant:
Sanofi, Paris, FR;
Inventors:
Laurent Bialy, Frankfurt am Main, DE;
Katrin Lorenz, Frankfurt am Main, DE;
Klaus Wirth, Frankfurt am Main, DE;
Klaus Steinmeyer, Frankfurt am Main, DE;
Gerhard Hessler, Frankfurt am Main, DE;
Assignee:
Sanofi, Paris, FR;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5383 (2006.01); C07D 471/04 (2006.01); C07D 498/04 (2006.01); C07D 513/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 498/04 (2013.01); C07D 513/04 (2013.01);
Abstract
The present invention relates in fused pyrroledicarboxamides of the formula (I), in which R1 to R9, X, m and n are as defined in claims. The compounds of the formula (I) are inhibitors of the acid-sensitive potassium channel TASK-1 and suitable for the treatment of TASK-1 channel-mediated diseases such as arrhythmias, in particular atrial arrhythmias like atrial fibrillation or atrial flutter, and respiratory disorders, in particular sleep-related respiratory disorders like sleep apnea, for example.