The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2018
Filed:
Feb. 06, 2014
Immunomet Therapeutics Inc., Cambridge, MA (US);
Chang Hee Min, Seoul, KR;
Yong Eun Kim, Daejeon, KR;
Byung Kyu Oh, Chungcheongnam-do, KR;
Ji Sun Lee, Daejeon, KR;
Hye Jin Heo, Daejeon, KR;
Ju Hoon Oh, Gangwon-do, KR;
Woong Cho, Daejeon, KR;
ImmunoMet Therapeutics Inc., Houston, TX (US);
Abstract
The present invention provides an N1-cyclic amine-N5-substituted biguanide derivative compound represented by Formula 1, a method of preparing the same and a pharmaceutical composition including the biguanide derivative or the pharmaceutically acceptable salt thereof as an active ingredient. The biguanide derivatives have an effect of inhibiting cancer cell proliferation, cancer metastasis and cancer recurrence by activation of AMPK, even when administered in a small dose compared with conventional drugs.