The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2018
Filed:
Jan. 06, 2017
Applicant:
Auspex Pharmaceuticals, Inc., La Jolla, CA (US);
Inventors:
Chengzhi Zhang, San Diego, CA (US);
Ralph Laufer, Tel Aviv, IL;
Assignee:
Auspex Pharmaceuticals, Inc., Frazer, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/86 (2006.01); A61K 45/06 (2006.01); A61K 31/403 (2006.01); A61K 31/4704 (2006.01);
U.S. Cl.
CPC ...
C07D 209/86 (2013.01); A61K 31/403 (2013.01); A61K 31/4704 (2013.01); A61K 45/06 (2013.01);
Abstract
Described are deuterium-substituted tetrahydrocarbazole compounds of Formulae I, II, or III which are inhibitors of sirtuin 1 (SIRT1). Also described are pharmaceutical compositions comprising the deuterium-substituted tetrahydrocarbazole compounds, and methods of use thereof.