The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2018
Filed:
Oct. 11, 2012
Applicant:
Emory University, Atlanta, GA (US);
Inventors:
Assignee:
Emory University, Atlanta, GA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); C08F 212/32 (2006.01); A61K 31/18 (2006.01); C07C 311/29 (2006.01); C09B 1/06 (2006.01); C09B 1/12 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07C 311/29 (2013.01); A61K 31/18 (2013.01); A61K 45/06 (2013.01); C07K 16/40 (2013.01); C09B 1/06 (2013.01); C09B 1/12 (2013.01); C07C 2603/24 (2017.05); C07K 2317/34 (2013.01);
Abstract
In certain embodiments, the disclosure relates to methods of treating or preventing a PGAM1 mediated condition such as cancer or tumor growth comprising administering an effective amount of PGAM1 inhibitor, for example, an anthracene-9,10-dione derivative to a subject in need thereof. In certain embodiments, the disclosure relates to methods of treating or preventing cancer, such as lung cancer, head and neck cancer, and leukemia, comprising administering a therapeutically effective amount of a pharmaceutical composition comprising a compound disclosed herein or pharmaceutically acceptable salt to a subject in need thereof.