The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2018
Filed:
Mar. 03, 2017
Rgenix, Inc., New York, NY (US);
Eduardo J. Martinez, Bryn Mawr, PA (US);
Andreas G. Grill, Saint James, NY (US);
Aniruddh Singh, Carteret, NJ (US);
Padmini Kavuru, Fitchburg, MA (US);
Nicholas D. Paschalides, Marlborough, MA (US);
Stephen A. Wald, Valley Cottage, NY (US);
Rgenix, Inc., New York, NY (US);
Abstract
The present invention relates to new pharmaceutical salts of β-GPA which exhibit improved physical properties. In particular, the invention relates to salts of β-GPA with improved flow properties (e.g., improved Carr's index and/or Hausner ratio) such as fumarate salts, succinate salts, and oxalate salts. The invention also relates to pharmaceutical compositions including a pharmaceutically effective amount of one or more salts of β-GPA, as well as methods of treating cancer including administration of a formulation including a β-GPA salt of the invention to a subject in need thereof.