The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 06, 2018

Filed:

Sep. 10, 2014
Applicants:

Universite Pierre ET Marie Curie, Paris, FR;

Centre National DE LA Recherche Scientifique, Paris, FR;

Ecole Pratique Des Hautes Etudes, Paris, FR;

Inventors:

Nadine Nassif, Paris, FR;

Frederic Gobeaux, Paris, FR;

Marie-Madeleine Giraud-Guille, Paris, FR;

Gervaise Mosser, Paris, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61L 27/46 (2006.01); A61L 27/24 (2006.01);
U.S. Cl.
CPC ...
A61L 27/46 (2013.01); A61L 2430/02 (2013.01);
Abstract

A method for preparing a synthetic material having an organic phase and a mineral phase which consists in preparing an initial acidic aqueous solution of collagen which is a precursor for the organic phase (I), and at least one aqueous solution of precursors for the mineral phase (II), and in precipitating the collagen by increasing the pH to a value of at least 7. The method includes the concentration of collagen in the acidic aqueous solution is at least 75 mg/ml and remains constant during said increase in pH. The mineral phase precursors have at least one calcium salt and at least one phosphate salt. The precipitation of the mineral phase (II) is carried out by bringing the mineral phase precursor solution into contact with the organic phase (I), the bringing into contact being carried out before or after the precipitation of the organic phase (I).


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