The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 06, 2018

Filed:

Jan. 03, 2013
Applicant:

Invictus Oncology Pvt. Ltd., Delhi, IN;

Inventors:

Shiladitya Sengupta, Waltham, MA (US);

Sazid Hussain, Delhi, IN;

Dipankar Pramanik, Delhi, IN;

Monideepa Roy, Delhi, IN;

Seikh Samad Hossain, Delhi, IN;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); A61K 47/68 (2017.01); A61K 47/00 (2006.01); A61K 31/282 (2006.01); C07F 15/00 (2006.01); A61K 47/50 (2017.01); A61K 47/60 (2017.01);
U.S. Cl.
CPC ...
A61K 47/48215 (2013.01); A61K 31/282 (2013.01); A61K 47/00 (2013.01); A61K 47/48561 (2013.01); A61K 47/48692 (2013.01); A61K 47/50 (2017.08); A61K 47/60 (2017.08); A61K 47/68 (2017.08); A61K 47/6803 (2017.08); A61K 47/6849 (2017.08); A61K 47/6883 (2017.08); C07F 15/0086 (2013.01);
Abstract

The present invention relates to ligand-targeted molecules and ligand drug conjugates (LDCs) comprising a ligand connected to a functional group, which is connected to a linker, which in turn is bonded to a drug. The LDCs of the present invention also comprise platinum coordination complex wherein the platinum is connected to the linker through monocarboxylato and O→Pt coordinate bonds. The present invention also relates to methods for preparing these ligand drug conjugates. The present invention further relates to methods for the treatment of tumours using the ligand drug conjugates of the present invention.


Find Patent Forward Citations

Loading…