The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 06, 2018

Filed:

Apr. 30, 2014
Applicant:

The Regents of the University of Colorado, a Body, Denver, CO (US);

Inventors:

Shapiro Leland, Denver, CO (US);

Eli C. Lewis, Be'er Sheva, IL;

Charles A. Dinarello, Boulder, CO (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/57 (2006.01); A61K 39/00 (2006.01); A61K 38/19 (2006.01); A61K 38/21 (2006.01); A61K 45/06 (2006.01); A61K 35/39 (2015.01); C07K 16/40 (2006.01); C07K 16/46 (2006.01);
U.S. Cl.
CPC ...
A61K 38/57 (2013.01); A61K 35/39 (2013.01); A61K 38/191 (2013.01); A61K 38/217 (2013.01); A61K 45/06 (2013.01); C07K 16/40 (2013.01); A61K 2039/505 (2013.01);
Abstract

Embodiments of the present invention illustrate methods of treating and preventing transplantation and side effects associated with transplantation. In particular, the present invention relates to compositions and methods for inhibition of graft rejection and promotion of graft survival. Thus, the invention relates to modulation of cellular activities, including graft rejection, promotion of graft survival, graft versus host rejection and conditions commonly associated with graft rejection. More particularly, the present invention relates to the inhibitory compounds comprising naturally occurring and man-made inhibitors of serine protease and inducers of other alpha1-antitrypsin activities.


Find Patent Forward Citations

Loading…