The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 06, 2018

Filed:

Nov. 01, 2012
Applicant:

Snu R&db Foundation, Seoul, KR;

Inventors:

Seung Hyun Han, Seoul, KR;

Ok-Jin Park, Seoul, KR;

Cheol-Heui Yun, Seoul, KR;

Assignee:

SNU R&DB FOUNDATION, Seoul, KR;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/05 (2006.01); A23L 33/18 (2016.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/05 (2013.01); A23L 33/18 (2016.08); A23V 2002/00 (2013.01); A61K 2039/5555 (2013.01); A61K 2039/6062 (2013.01);
Abstract

The present invention relates to a bone regeneration or bone formation promoting pharmaceutical composition comprising muramyl dipeptide, an analog thereof, a derivative thereof or a pharmaceutically acceptable salt thereof. In contrast to existing passive therapeutic agents which center on bone absorption suppression based on mechanisms for reducing osteoclast functionality, the composition comprising muramyl dipeptide of the present invention promotes the differentiation of osteoblasts, which are bone forming cells, and can advantageously be used in various diseases where bone formation is required as an active therapeutic agent that does not affect osteoclast.


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