The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2018
Filed:
Mar. 14, 2014
University of Maryland Eastern Shore, Princess Anne, MD (US);
Thomas Jefferson University, Philadelphia, PA (US);
University of Maryland, Baltimore, Baltimore, MD (US);
Vincent C. O. Njar, Glen Burnie, MD (US);
Lalji K. Gediya, Gaithersburg, MD (US);
Puranik Purushottamachar, Gaithersburg, MD (US);
Abhijit Godbole, Macungie, PA (US);
Andrew Kwegyir-Afful, Severn, MD (US);
Tadas Vasaitis, Salisbury, MD (US);
University of Maryland, Baltimore, Baltimore, MD (US);
University of Maryland Eastern Shore, Princess Anne, MD (US);
Thomas Jefferson University, Philadelphia, PA (US);
Abstract
The present disclosure provides the design and synthesis of novel steroidal compounds that cause down-regulation of the androgen receptor (AR), both full length and splice variant. The compounds are potential agents for the treatment of all forms of prostate cancer and other diseases that depend on functional AR.