The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 06, 2018

Filed:

Jun. 26, 2017
Applicant:

Macau University of Science and Technology, Macau, CN;

Inventors:

Xiao Jun Yao, Macau, CN;

Lai Han Elaine Leung, Macau, CN;

Liang Liu, Macau, CN;

Xing Xing Fan, Macau, CN;

Chun Xie, Macau, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/428 (2006.01); G01N 33/574 (2006.01); C07D 277/72 (2006.01); C07K 14/47 (2006.01); C12Q 1/68 (2006.01); G01N 33/68 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/428 (2013.01); C07D 277/72 (2013.01); C07K 14/47 (2013.01); C12Q 1/6886 (2013.01); G01N 33/57423 (2013.01); G01N 33/57484 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01); C12Q 2600/112 (2013.01); G01N 33/574 (2013.01); G01N 33/68 (2013.01);
Abstract

One example embodiment relates to a method of treating non-small cell lung cancer by administering a compound of formula (I) to a patient. Another example embodiment relates to a method of inhibiting progress of tumor growth in a patient with cancer, wherein tumor cells of the cancer have a mutant V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) gene, and the method includes administering to the patient the compound with the following formula I:


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