The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 06, 2018

Filed:

May. 09, 2016
Applicant:

Egalet Ltd., London, GB;

Inventors:

Gina Fischer, Vaerløse, DK;

Daniel Bar-Shalom, Kokkedal, DK;

Lillian Slot, Virum, DK;

Christine Andersen, Vedbaek, DK;

Assignee:

EGALET LTD., London, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/70 (2006.01); A61K 9/00 (2006.01); A61K 31/485 (2006.01);
U.S. Cl.
CPC ...
A61K 9/70 (2013.01); A61K 9/0053 (2013.01); A61K 9/0092 (2013.01); A61K 31/485 (2013.01);
Abstract

A oral pharmaceutical composition for controlled release of an opioid from a pharmaceutical composition is described that comprises (i) an erodible matrix composition comprising a mixture of (a) a polymer or a mixture of polymers (b) an opioid, and optionally, (c) one or more pharmaceutically acceptable excipients; and (ii) a single, substantially insoluble in and impermeable coating having two openings exposing at least one surface of the matrix, and comprising one or more polymers. The composition exhibits controlled release of the opioid by erosion of the matrix and exhibits a zero order release profile wherein about 75% w/w of the opioid is released from the composition within 4-10 hours when tested in a dissolution test as described herein.


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