The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 06, 2018

Filed:

Jul. 15, 2013
Applicant:

Diagnostic Biochips, Inc., Glen Burnie, MD (US);

Inventors:

Brian Jamieson, Glen Burnie, MD (US);

Mary Emma Gorham Bigelow, Glen Burnie, MD (US);

Assignee:

DIAGNOSTIC BIOCHIPS, INC., Glen Burnie, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/1473 (2006.01); A61N 1/36 (2006.01); A61B 5/00 (2006.01); A61B 5/145 (2006.01); A61B 5/0476 (2006.01); A61B 5/04 (2006.01); A61N 1/05 (2006.01); B82Y 15/00 (2011.01);
U.S. Cl.
CPC ...
A61B 5/14735 (2013.01); A61B 5/04001 (2013.01); A61B 5/0476 (2013.01); A61B 5/14546 (2013.01); A61B 5/4836 (2013.01); A61B 5/4845 (2013.01); A61B 5/4848 (2013.01); A61B 5/6852 (2013.01); A61B 5/6876 (2013.01); A61N 1/0534 (2013.01); A61N 1/36139 (2013.01); A61B 2562/028 (2013.01); A61B 2562/125 (2013.01); A61N 1/0529 (2013.01); B82Y 15/00 (2013.01);
Abstract

Certain embodiments comprise an implantable probe for rapid measurement of multiple neurochemicals on the cellular scale in the brain. Rapid detection of multiple chemicals in vivo (animal or humans) may provide an improved understanding of acute changes in neurochemicals that occur over several seconds. The neurotransmitter chemical sensing platform may provide for continuous in vivo sensing in trials of psychoactive drugs in the laboratory animal market. The high spatial resolution of the probe may allow for chemical detection around small groups of neurons, which may help to isolate the endogenous activity of different neuron types due to disease states. Neurochemical detection may also be used to measure tissue response to exogenous stimuli, such as pharmacodynamics of drugs. The high temporal and spatial resolutions and multi-neurochemical sensing of the probe may allow for detailed studies on in vivo brain response to both endogenous and exogenous stimuli.


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