The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 06, 2018

Filed:

Feb. 04, 2013
Applicants:

Leah Tolosa, Columbia, MD (US);

Xudong GE, Ellicott City, MD (US);

Yordan Kostov, Columbia, MD (US);

Michael Tolosa, Columbia, MD (US);

Govind Rao, Ellicott City, MD (US);

Inventors:

Leah Tolosa, Columbia, MD (US);

Xudong Ge, Ellicott City, MD (US);

Yordan Kostov, Columbia, MD (US);

Michael Tolosa, Columbia, MD (US);

Govind Rao, Ellicott City, MD (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 5/145 (2006.01); A61B 10/00 (2006.01); B01L 3/00 (2006.01); G01N 33/542 (2006.01); A61B 5/15 (2006.01);
U.S. Cl.
CPC ...
A61B 5/14532 (2013.01); A61B 10/0045 (2013.01); B01L 3/5029 (2013.01); G01N 33/542 (2013.01); A61B 5/15 (2013.01); A61B 5/150343 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/0816 (2013.01);
Abstract

Systems and methods for determining an in vivo concentration of a small molecule substance of interest is provided that takes advantage of the semi-permeable nature of skin, which allows small molecules to passively diffuse through the skin and onto the skin surface. The systems and methods of the present invention allow for the collection of these small molecules that have passively diffused through the skin without skin disruption or breaking of the skin. The systems and methods of the present invention are noninvasive, painless and safe even for delicate newborns, and are particularly suited for the determination of blood glucose in newborns and infants in a noninvasive manner.


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