The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2018
Filed:
Mar. 01, 2013
Applicants:
Ludwig Institute for Cancer Research Ltd., New York, NY (US);
The Chancellor, Masters and Scholars of the University of Oxford, Oxford, GB;
Assignee:
LUDWIG INSTITUTE FOR CANCER RESEARCH LTD., Zurich, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); C07K 16/18 (2006.01); C07K 14/47 (2006.01); C07K 16/30 (2006.01); C07K 16/44 (2006.01); G06F 19/00 (2011.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57496 (2013.01); C07K 14/4703 (2013.01); C07K 14/4746 (2013.01); C07K 16/18 (2013.01); C07K 16/30 (2013.01); C07K 16/44 (2013.01); G06F 19/3431 (2013.01); A61K 2039/505 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01); G01N 2333/4704 (2013.01); G01N 2333/4748 (2013.01); G01N 2440/14 (2013.01); G01N 2800/56 (2013.01);
Abstract
Described herein are methods of evaluating metastatic potential of a cancer based on the phosphorylation state and/or intracellular localization of iASPP. Therapeutic regimens designed based on the results of the diagnostic methods are also provided.