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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9879297 B1

PDFFull Text
Date of Patent:
Jan. 30, 2018

Filed:

Jun. 28, 2012

High efficiency gene transfer and expression in mammalian cells by amultiple transfection procedure of mar sequences

Applicants:

Mermod Nicolas, Buchillon, CH;

Pierre Alain Girod, Lausanne, CH;

Philipp Bucher, Lausanne, CH;

Duc-quang Nguyen, Saint Prex, CH;

David Calabrese, Lausanne, CH;

Damien Saugy, Lausanne, CH;

Stefania Puttini, Lausanne, CH;

Inventors:

Mermod Nicolas, Buchillon, CH;

Pierre Alain Girod, Lausanne, CH;

Philipp Bucher, Lausanne, CH;

Duc-Quang Nguyen, Saint Prex, CH;

David Calabrese, Lausanne, CH;

Damien Saugy, Lausanne, CH;

Stefania Puttini, Lausanne, CH;

Assignee:

SELEXIS SA, Plan-les-Ouates, CH;

Attorneys:

Agris & Von Natzmer, LLP

Joyce Von Natzmer

Primary Examiner:

Channing S Mahatan

Int. Cl.
CPC ...
C12P 21/00 (2006.01); C12N 15/09 (2006.01); C12N 15/10 (2006.01); C12N 15/11 (2006.01); C12N 15/63 (2006.01); G06F 19/12 (2011.01); G06F 19/16 (2011.01); G06F 19/22 (2011.01);
U.S. Cl.
CPC ...
C12P 21/00 (2013.01); C12N 15/1089 (2013.01); C12N 15/11 (2013.01); C12N 15/63 (2013.01); G06F 19/12 (2013.01); G06F 19/16 (2013.01); G06F 19/22 (2013.01);
Abstract

The present invention relates to purified and isolated DNA sequences having protein production increasing activity and more specifically to the use of matrix attachment regions (MARs) for increasing protein production activity in a eukaryotic cell. Also disclosed is a method for the identification of said active regions, in particular MAR nucleotide sequences, and the use of these characterized active MAR sequences in a new multiple transfection method.

Find Patent Forward Citations

Nicolas, Mermod. (2018). High efficiency gene transfer and expression in mammalian cells by amultiple transfection procedure of mar sequences (U.S. Patent No. 9879297). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9879297

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