The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2018
Filed:
Mar. 12, 2009
Applicants:
Mark Lackner, South San Francisco, CA (US);
Lukas C. Amler, Foster City, CA (US);
Guy Cavet, Burlingame, CA (US);
Carol O'brien, Pacifica, CA (US);
Ajay Pandita, Redwood City, CA (US);
Inventors:
Mark Lackner, South San Francisco, CA (US);
Lukas C. Amler, Foster City, CA (US);
Guy Cavet, Burlingame, CA (US);
Carol O'Brien, Pacifica, CA (US);
Ajay Pandita, Redwood City, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12N 15/113 (2010.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1138 (2013.01); A61K 47/48407 (2013.01); A61K 47/48584 (2013.01); C12Q 1/6886 (2013.01); C12N 2310/14 (2013.01); C12Q 2600/106 (2013.01);
Abstract
Methods and compositions are provided to determine if a cancer is resistant to treatment with anti-mitotic agents, including treatment with T-DM1. The methods relate to determining if the ABCC3 gene is amplified and/or overexpressed in the cancer.