The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2018
Filed:
Jan. 27, 2015
Applicant:
Novo Nordisk A/s, Bagsvaerd, DE;
Inventors:
Peter Andreas Nicolai Reumert Wagtmann, Rungsted Kyst, DE;
Ivan Svendsen, Smorum, DE;
Rozana Sten, Malmo, SE;
Lene Hjorth Alifrangis, Viby, DE;
Rune Viig Overgaard, Copenhagen, DE;
Assignee:
NOVO NORDISK A/S, Bagsvaerd, DE;
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C12P 21/08 (2006.01); C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); A61K 39/3955 (2013.01); A61K 39/39541 (2013.01); C07K 16/2803 (2013.01); A61K 2039/505 (2013.01); A61K 2039/545 (2013.01);
Abstract
A novel IgG4 isotype anti-KIR antibody, novel formulations of this and other IgG4 anti-KIR antibodies, and methods of using such formulations are provided. Also described are compositions, formulations, dosages, and administration regimens suitable for NK cell activation and therapeutic applications of anti-KIR antibodies, as well as kits comprising one or more anti-KIR antibodies with instructions for use in treating cancer.