The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2018
Filed:
Feb. 06, 2014
Yokohama City University, Yokohama-shi, JP;
Chiome Bioscience Inc., Tokyo, JP;
Yoshio Goshima, Yokohama, JP;
Fumio Nakamura, Yokohama, JP;
Naoya Yamashita, Yokohama, JP;
Hidetaka Seo, Tokyo, JP;
Shuichi Hashimoto, Tokyo, JP;
Koji Murakami, Tokyo, JP;
Naoki Takahashi, Chiba, JP;
Yukie Sasakura, Tokyo, JP;
Yokohama City University and Chiome Bioscience Inc., Yokohama-shi, Kanagawa, Tokyo, JP;
Abstract
The present invention mainly addresses the problem of providing an antibody against semaphorin 3A protein, said antibody enabling effective prevention and/or treatment of a disease, in which Sema 3A protein participates, such as a neurodegenerative disease, autoimmune disease, inflammatory disease, cancer, infectious disease, etc. or disseminated intravascular coagulation syndrome. An anti-Sema 3A antibody comprising CDRs having specific amino acid sequences (SEQ ID NOS: 1-6, 60-62, 64-66, 68-70, 72-74, 76-78, 80-82, 84-86 and 88-90) enables effective prevention and/or treatment of a disease, in which Sema 3A protein participates, such as a neurodegenerative disease, autoimmune disease, inflammatory disease, cancer, infectious disease, etc. or disseminated intravascular coagulation syndrome and, therefore, remarkably ameliorates symptoms associated with such a disease.