The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2018
Filed:
Apr. 06, 2017
Daiichi Sankyo Company, Limited, Chuo-ku, Tokyo, JP;
Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA (US);
Shojiro Miyazaki, Shinagawa-ku, JP;
Yuko Yamamoto, Shinagawa-ku, JP;
Keisuke Suzuki, Shinagawa-ku, JP;
Masaharu Inui, Shinagawa-ku, JP;
Masanori Izumi, Shinagawa-ku, JP;
Kaori Soma, Shinagawa-ku, JP;
Anthony Pinkerton, La Jolla, CA (US);
Taeko Shinozaki, Shinagawa-ku, JP;
Daiichi Sankyo Company, Limited, Chuo-ku, JP;
Sandford Burnham Prebys Medical Discovery Institute, La Jolla, CA (US);
Abstract
The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I): wherein Rrepresents a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, Rand Rare the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, Rand Rare the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, Rrepresents a hydrogen atom or the like, each Rmay be the same or different and may each represent an optionally substituted C1-6 alkoxy group or the like, X represents —CH═, —C(—R)═, or —N═, and m represents 1 to 4, or a pharmacologically acceptable salt thereof.