The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2018
Filed:
Jan. 15, 2014
Applicant:
Merck Patent Gmbh, Darmstadt, DE;
Inventors:
Thomas E. Richardson, Durham, NC (US);
Nadia Brugger, Cambridge, MA (US);
Justin Potnick, Acton, MA (US);
Assignee:
Merck Patent GMBH, Darmstadt, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 215/06 (2006.01); C07D 409/06 (2006.01); A61K 45/06 (2006.01); A61K 31/437 (2006.01); A61K 31/47 (2006.01); C07D 215/12 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/437 (2013.01); A61K 31/47 (2013.01); A61K 45/06 (2013.01); C07D 215/06 (2013.01); C07D 215/12 (2013.01); C07D 409/06 (2013.01);
Abstract
The present invention relates to novel acetylene derivatives as positive allosteric modulators for modulating metabotropic glutamate receptor subtype 4 (mGluR4) and/or altering glutamate level or glutamatergic signalling.