The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2018
Filed:
May. 13, 2015
Memorial Sloan Kettering Cancer Center, New York, NY (US);
Gabriela Chiosis, New York, NY (US);
Yanlong Kang, Plainsboro, NJ (US);
Hardik J. Patel, Kew Gardens, NY (US);
Maulik Patel, New York, NY (US);
Stefan Ochiana, Chevy Chase, MD (US);
Anna Rodina, New York, NY (US);
Tony Taldone, Forest Hills, NY (US);
Liza Shrestha, New York, NY (US);
Memorial Sloan Kettering Cancer Center, New York, NY (US);
Abstract
The present invention provides compounds I and II and compositions thereof for use in the modulation of Hsp70. In some embodiments, the present invention provides a method for inhibiting Hsp70 activity. In some embodiments, the present invention provides a method of treating a subject suffering from or susceptible to a disease, disorder, or condition responsive to Hsp70 inhibition comprising administering to the subject a therapeutically effective amount of a provided compound. In some embodiments, the present invention provides a method for treating or preventing cancer in a subject suffering therefrom, comprising administering to a patient in need thereof a therapeutically effective amount of a provided compound.