The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2018
Filed:
May. 17, 2013
Applicant:
Tufts Medical Center, Inc., Boston, MA (US);
Inventor:
Athan Kuliopulos, Winchester, MA (US);
Assignee:
Tufts Medical Center, Inc., Boston, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/08 (2006.01); A61K 47/26 (2006.01); A61K 47/48 (2006.01); A61K 9/00 (2006.01); A61K 9/107 (2006.01); A61K 9/19 (2006.01); A61K 38/17 (2006.01); A61K 45/06 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
A61K 47/488 (2013.01); A61K 9/0019 (2013.01); A61K 9/1075 (2013.01); A61K 9/19 (2013.01); A61K 38/08 (2013.01); A61K 38/177 (2013.01); A61K 45/06 (2013.01); A61K 47/26 (2013.01); A61K 47/48038 (2013.01); A61K 47/48046 (2013.01); A61K 47/48238 (2013.01); C07K 14/705 (2013.01);
Abstract
In certain embodiments, this disclosure relates to pharmaceutical formulations for polypeptide and lipophilic moiety conjugates suitable for injection into humans and other animals and methods of preparation. In certain embodiments, the disclosure relates to a method of preparing the formulation comprising lyophilizing, solubilizing in ammonium acetate, filtering to create mono-disperse particles, re-lyophilizing, and solubilizing the micelles in a dextrose solution for injection.