The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2018
Filed:
Feb. 26, 2014
Jiangsu Theravac Bio-pharmaceutical Co., Ltd., Nanjing, Jiangsu, CN;
Sean Xiaohan Du, Nanjing, CN;
Jun Ge, Nanjing, CN;
Xiaoqian Zhuang, Nanjing, CN;
Tong Zhou, Nanjing, CN;
Jianqiang Li, Nanjing, CN;
Cuiling Song, Nanjing, CN;
Ying Sun, Nanjing, CN;
Meiju Wang, Nanjing, CN;
Yue Gu, Nanjing, CN;
Honglin Sun, Nanjing, CN;
Zhenxing Xu, Nanjing, CN;
Hongying Huang, Nanjing, CN;
Xiaoxiao Chen, Nanjing, CN;
JIANGSU THERAVAC BIO-PHARMACEUTICAL CO., LTD., Nanjing, CN;
Abstract
Disclosed is a composition comprising: i) HBsAg, a fragment thereof, a variant thereof, or the mixture of at least two of them, ii) HBcAg1-X, a fragment thereof, a variant of the antigen or the antigen fragment, or the mixture of at least two of them, wherein X is an integer of from 149 to 183, iii) CpG-ODN, 21 bases long, which is a phosphorothioate oligonucleotide and includes two or more copies of 5'-NTCGTT-3′ motifs. The use of the composition in the treatment of HBV-infection and HBV-induced diseases, and the therapy methods of HBV-infection and HBV-induced diseases are also disclosed.