The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 30, 2018

Filed:

Oct. 09, 2013
Applicants:

President and Fellows of Harvard College, Cambridge, MA (US);

Newsouth Innovations Pty Limited, Sydney, AU;

Inventors:

David A. Sinclair, Chestnut Hill, MA (US);

Ana P. Gomes, New York, NY (US);

Lindsay Wu, Coogee, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); A61K 31/70 (2006.01); A61K 31/7064 (2006.01); A61K 38/45 (2006.01); A61K 48/00 (2006.01); A61K 31/706 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7064 (2013.01); A61K 38/45 (2013.01); A61K 48/005 (2013.01); A01K 2217/075 (2013.01); A01K 2227/105 (2013.01); A01K 2267/035 (2013.01); A61K 31/706 (2013.01); C12Y 204/02012 (2013.01); C12Y 207/07001 (2013.01);
Abstract

Disclosed herein are novel compositions and methods for the treatment of age-related diseases, mitochondrial diseases, the improvement of stress resistance, the improvement of resistance to hypoxia and the extension of life span. Also described herein are methods for the identification of agents useful in the foregoing methods. Methods and compositions are provided for the treatment of diseases or disorders associated with mitochondrial dysfunction. The invention relates to methods for treatment and prevention of cancer by administering agents that increase levels of NAD+, such as NAD+ precursors or agents involved in NAD+ biosynthesis.


Find Patent Forward Citations

Loading…