The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2018
Filed:
Jan. 04, 2014
Applicant:
Max-planck-gesellschaft Zur Förderung Der Wissenschaften E.v., Munich, DE;
Inventors:
Marcelo Paez-Pereda, Munich, DE;
Guenter Stalla, Holzkirchen, DE;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/357 (2006.01); C07D 407/04 (2006.01); A61K 36/28 (2006.01); A61K 45/06 (2006.01); A61K 31/573 (2006.01); A61K 31/7048 (2006.01);
U.S. Cl.
CPC ...
A61K 31/357 (2013.01); A61K 31/573 (2013.01); A61K 31/7048 (2013.01); A61K 36/28 (2013.01); A61K 45/06 (2013.01); C07D 407/04 (2013.01);
Abstract
The present invention relates to C-terminal HSP90 inhibitors, like silibinin, novobiocin and derivatives thereof, stereoisomeric forms, prodrugs, solvates, hydrates and/or pharmaceutically acceptable salts of these compounds as well as pharmaceutical compositions containing at least one of these compounds together with pharmaceutically acceptable carrier, excipient and/or diluents. Said compounds and its compositions have been identified as useful for the treatment of pituitary adenomas such as corticotroph adenomas, lactotroph adenomas, somatotroph adenomas and thyrotroph adenomas.