The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 2018
Filed:
Feb. 02, 2016
Applicant:
Fluidigm Canada Inc., Markham, CA;
Inventor:
Olga Ornatsky, Richmond Hill, CA;
Assignee:
Fluidigm Canada Inc., Markham, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/42 (2006.01); G01N 33/68 (2006.01); C12Q 1/48 (2006.01); G01N 33/569 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6848 (2013.01); C12Q 1/42 (2013.01); C12Q 1/485 (2013.01); G01N 33/569 (2013.01); G01N 33/58 (2013.01); G01N 33/6842 (2013.01); G01N 2333/916 (2013.01); G01N 2333/91205 (2013.01); G01N 2440/14 (2013.01); G01N 2458/15 (2013.01); G01N 2560/00 (2013.01); Y10S 435/975 (2013.01);
Abstract
Methods and kits for enzymes involved in post-translational modifications are provided. The methods employ elemental analysis, including ICP-MS. The methods allow for the convenient and accurate analysis of post-translation modifications of substrates by enzymes involved in post-translational modifications, including kinase and phosphatase enzymes. Kits may include an element tag for directly tagging an affinity product that recognizes phosphorylated substrates, as well as a non-phosphorylated substrate or an expression plasmid.