The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 23, 2018

Filed:

Apr. 26, 2017
Applicant:

Novozymes, Inc., Davis, CA (US);

Inventors:

Debbie Yaver, Davis, CA (US);

Peter Nham, Sacramento, CA (US);

Assignee:

Novozymes, Inc., Davis, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/80 (2006.01); C12N 9/06 (2006.01); C12N 9/00 (2006.01); C12N 9/58 (2006.01); C12N 9/20 (2006.01);
U.S. Cl.
CPC ...
C12N 15/80 (2013.01); C12N 9/0044 (2013.01); C12N 9/20 (2013.01); C12N 9/58 (2013.01); C12N 9/93 (2013.01); C12Y 107/01003 (2013.01); C12Y 301/01003 (2013.01); C12Y 304/21004 (2013.01); C12Y 603/04002 (2013.01);
Abstract

The present invention relates to methods for producing a biological substance, comprising: (a) cultivating a fungal host cell in a medium conducive for the production of the biological substance, wherein the fungal host cell comprises a first nucleic acid sequence encoding the biological substance operably linked to a second nucleic acid sequence comprising a promoter variant selected from the group consisting of SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 10, SEQ ID NO: 11, and SEQ ID NO: 12; and a subsequence thereof; and hybrid and tandem promoters thereof; and (b) isolating the biological substance from the cultivation medium. The present invention also relates to the isolated promoter variants and to constructs, vectors, and fungal host cells comprising the promoter variants operably linked to nucleic acid sequences encoding biological substances.


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