The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 23, 2018

Filed:

Nov. 23, 2016
Applicant:

Tagcyx Biotechnologies, Yokohama-shi, Kanagawa, JP;

Inventors:

Ichiro Hirao, Tokyo, JP;

Michiko Hirao, Tokyo, JP;

Rie Yamashige, Saitama, JP;

Shigeyuki Yokoyama, Saitama, JP;

Assignee:

Tagcyx Biotechnologies, Kanagawa, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/115 (2010.01); A61K 48/00 (2006.01); C12N 15/10 (2006.01); C12Q 1/68 (2006.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01); A61K 48/00 (2013.01); C12N 15/1048 (2013.01); C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12Q 1/6869 (2013.01); G01N 33/5308 (2013.01); C12N 2310/12 (2013.01); C12N 2310/16 (2013.01); C12N 2310/33 (2013.01); C12N 2310/331 (2013.01); C12N 2320/13 (2013.01);
Abstract

An object of the present invention is to develop and provide a method for efficiently producing a nucleic acid aptamer, particularly, a DNA aptamer, having higher specificity and binding activity against a target substance than those of nucleic acid aptamers obtained by conventional methods. The present invention provides a transcribable or replicable nucleic acid aptamer comprising a natural nucleotide and a non-natural nucleotide having an artificial base-pairable artificial base. The present invention also provides a method for sequencing a non-natural nucleotide-containing single-stranded nucleic acid molecule selected from a single-stranded nucleic acid library.


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