The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 23, 2018

Filed:

Feb. 23, 2016
Applicant:

Single Cell Technology, Inc., San Jose, CA (US);

Inventors:

Chun-Nan Chen, San Jose, CA (US);

James O. Bowlby, San Jose, CA (US);

Richard Aleck Jorgensen, San Jose, CA (US);

Mark Jay Shlomchik, Woodbridge, CT (US);

Assignee:

SINGLE CELL TECHNOLOGY, INC., San Jose, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 30/04 (2006.01); C40B 40/06 (2006.01); G01N 33/00 (2006.01); C12N 15/10 (2006.01); C07K 16/28 (2006.01); C07K 16/40 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1065 (2013.01); C07K 16/2896 (2013.01); C07K 16/40 (2013.01); C07K 2317/56 (2013.01);
Abstract

The invention is a methodology which makes it possible to select from a very large number of cells, a single cell or cells of interest and obtain specific information from those cells in a rapid and efficient manner. As an example of the methodology, a large number of antibody producing cells such as plasma cells are separated so that these individual antibody producing plasma cells are placed in individual wells. The cells are allowed to produce antibodies and the antibodies in the wells are then contacted with a protein bound to a solid surface such as a well top. The protein universally and specifically binds antibodies in the wells. The surface or well tray top includes addresses configured such that each address is specifically related to one of the individual wells containing a cell producing antibodies.


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