The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 2018
Filed:
Oct. 27, 2015
Applicant:
Biomarin Pharmaceutical Inc., Novato, CA (US);
Inventors:
Assignee:
BIOMARIN PHARMACEUTICAL INC., Novato, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/16 (2006.01); C12Q 1/34 (2006.01); C12Q 1/44 (2006.01); G01N 33/68 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/16 (2013.01); C12Q 1/34 (2013.01); C12Q 1/44 (2013.01); G01N 33/6893 (2013.01); A01K 2217/075 (2013.01); A01K 2267/035 (2013.01); A61K 38/00 (2013.01); C12Y 301/06014 (2013.01); G01N 2333/924 (2013.01); G01N 2400/40 (2013.01); G01N 2500/04 (2013.01); G01N 2800/04 (2013.01);
Abstract
This invention provides compositions of active highly phosphorylated lysosomal sulfatase enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal sulfatase enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the lysosomal sulfatase enzyme.