The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 2018
Filed:
Mar. 31, 2015
Applicant:
Genentech, Inc., South San Francisco, CA (US);
Inventors:
Mary Keir, South San Francisco, CA (US);
Gaik Wei Tew, South San Francisco, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12P 19/34 (2006.01); C07K 16/28 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2839 (2013.01); C12Q 1/6883 (2013.01); G01N 33/6872 (2013.01); G01N 33/6893 (2013.01); C07K 2317/24 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/7051 (2013.01); G01N 2333/70546 (2013.01); G01N 2800/06 (2013.01); G01N 2800/065 (2013.01); G01N 2800/52 (2013.01);
Abstract
Biomarkers predictive of responsiveness to integrin beta7 antagonists, including anti-beta7 integrin subunit antibodies, and methods of using such biomarkers are provided. In addition, methods of treating gastrointestinal inflammatory disorders such as inflammatory bowel diseases including ulcerative colitis and Crohn's disease are provided. Also provided are methods of using such predictive biomarkers for the treatment of inflammatory bowel diseases including ulcerative colitis and Crohn's disease.