The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 2018
Filed:
Jul. 16, 2014
Genentech, Inc., South San Francisco, CA (US);
Jane Grogan, San Francisco, CA (US);
Robert J. Johnston, San Francisco, CA (US);
Bryan Irving, San Francisco, CA (US);
Jason Hackney, San Carlos, CA (US);
Xin Yu, South San Francisco, CA (US);
Dan Eaton, San Rafael, CA (US);
Kristin Bowles, South San Francisco, CA (US);
Laetitia Comps-Agrar, Foster City, CA (US);
Genentech, Inc., South San Francisco, CA (US);
Abstract
The present invention describes combination treatment comprising a PD-1 axis binding antagonist and an agent that decreases or inhibits TIGIT expression and/or activity and methods for use thereof, including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer or chronic infection.