The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 23, 2018

Filed:

Sep. 14, 2012
Applicants:

Tom Tong Lee, San Diego, CA (US);

Michael J. Fitch, Carlsbad, CA (US);

Kevin Lai, San Diego, CA (US);

Peter Flynn, San Diego, CA (US);

Monica Bennett, San Diego, CA (US);

Inventors:

Tom Tong Lee, San Diego, CA (US);

Michael J. Fitch, Carlsbad, CA (US);

Kevin Lai, San Diego, CA (US);

Peter Flynn, San Diego, CA (US);

Monica Bennett, San Diego, CA (US);

Assignee:

Fate Therapeutics, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); C07K 14/475 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/47 (2013.01); C07K 14/475 (2013.01); A61K 38/00 (2013.01); C07K 2319/02 (2013.01); C07K 2319/20 (2013.01); C07K 2319/21 (2013.01); C07K 2319/30 (2013.01); C07K 2319/40 (2013.01); C07K 2319/41 (2013.01); C07K 2319/42 (2013.01); C07K 2319/43 (2013.01); C07K 2319/50 (2013.01);
Abstract

The invention provides novel Wnt polypeptides that have improved production characteristics, solubility, systemic delivery, and tissue uptake, and polynucleotides encoding the Wnt polypeptides of the invention. The Wnt polypeptides of the invention can be used therapeutically, such as, for example, in methods of preventing or treating muscle loss and/or promoting muscle hypertrophy and growth.


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