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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9873693 B1

PDFFull Text
Date of Patent:
Jan. 23, 2018

Filed:

Jul. 10, 2014

Methods of treatment using pyridinonyl pdk1 inhibitors

Applicants:

Sunesis Pharmaceuticals, Inc., South San Franciso, CA (US);

Millennium Pharmaceuticals, Inc., Cambridge, MA (US);

Inventors:

Kenneth Egnard Lind, Arlington, MA (US);

Kathy Cao, Sunnyvale, CA (US);

Edward Yin-shiang Lin, Chestnut Hill, MA (US);

Thinh Ba Nguyen, Santa Clara, CA (US);

Bradley T. Tangonan, San Francisco, CA (US);

Daniel A. Erlanson, San Francisco, CA (US);

Kevin Guckian, Marlborough, MA (US);

Robert Lowell Simmons, San Francisco, CA (US);

Wen-cherng Lee, Lexington, MA (US);

Lihong Sun, Lexington, MA (US);

Stig Hansen, Kensington, CA (US);

Nuzhat Pathan, San Diego, CA (US);

Lei Zhang, Cheshire, CT (US);

Assignees:

Sunesis Pharmaceuticals, Inc., South San Francisco, CA (US);

Millennium Pharmaceuticals, Inc., Cambridge, MA (US);

Attorney:

Choate, Hall & Stewart LLP

Primary Examiner:

Matthew Coughlin

Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/506 (2006.01); A61K 31/519 (2006.01); A61K 31/4985 (2006.01); A61K 31/444 (2006.01); A61K 31/4439 (2006.01); A61K 31/4436 (2006.01); A61K 31/443 (2006.01); A61K 31/4412 (2006.01); C07D 487/04 (2006.01); C07D 471/04 (2006.01); C07D 417/14 (2006.01); C07D 417/12 (2006.01); C07D 413/14 (2006.01); C07D 413/12 (2006.01); C07D 409/14 (2006.01); C07D 409/12 (2006.01); C07D 405/14 (2006.01); C07D 405/12 (2006.01); C07D 401/14 (2006.01); C07D 401/12 (2006.01); C07D 211/86 (2006.01); C07D 213/64 (2006.01); C07D 407/14 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/443 (2013.01); A61K 31/444 (2013.01); A61K 31/4412 (2013.01); A61K 31/4436 (2013.01); A61K 31/4439 (2013.01); A61K 31/4985 (2013.01); A61K 31/506 (2013.01); A61K 31/519 (2013.01); A61K 31/5377 (2013.01); C07D 211/86 (2013.01); C07D 213/64 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 407/14 (2013.01); C07D 409/12 (2013.01); C07D 409/14 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 487/04 (2013.01);
Abstract

The present invention provides pyridinonyl PDK1 inhibitors and methods of treating cancer using the same.

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